作者: Zhongxin Zhou , Zheng Yin , Xiaoqing Hu
DOI: 10.1002/BAB.1225
关键词: Citrinin 、 Hydrolysate 、 Corncob 、 Pigment 、 Substrate (chemistry) 、 Chemistry 、 Fermentation 、 Caprylic acid 、 Monascus 、 Biochemistry 、 Food science 、 Biotechnology 、 Process Chemistry and Technology 、 Molecular medicine 、 Applied Microbiology and Biotechnology 、 Bioengineering 、 Drug discovery 、 Biomedical engineering 、 General Medicine
摘要: Monascus pigment has traditionally been produced by the fermentation of using rice powder or glucose as a culture substrate. Submerged can produce stable yield and control accumulation by-product, citrinin, which then be more easily removed. To reduce cost submerged fermentation, feasibility corncob hydrolysate an alternative substrate was investigated. Results showed that, when compared with conventional medium, medium equivalent without stimulating citrinin accumulation. Furthermore, cultivation conditions were optimized to enhance production decrease synthesis. When sp. cultured under dark in presence caprylic acid, increased 25.8 ± 0.8 UA500 /mL, higher than that achieved (24.0 ± 0.9 UA500 /mL), those obtained previously reported fermentations same unit; on other hand, decreased 26.2 ± 1.9 µg/L, significantly lower generated (44.3 ± 2.2 µg/L) fermentations. Thus, proved efficient for through significant advantages over