Clinical Applications for Targeted Therapy in Bladder Cancer

摘要: The tremendous amount of data accumulated through genomics, proteomics, and meta-bolomic technologies has not led to a definitive understanding the mechanisms underlying cancer. challenge remains as how integrate all relevant knowledge in systematic manner so that researchers can gain needed devise best therapeutic diagnostic strategies. Human transitional cell carcinoma bladder is genetically heterogeneous, it surrounded by complex tissue microenvironment involving vasculature, stromal cells, connective tissue. One most challenging problems facing cancer lack correlation between vitro lines animal tumor models human vivo tumors. A few promising approaches are being devised will help address this issue coming years. such approach measurements molecular levels receptors, ligands, pathways components, on, directly tumors imaging, or proteomic profiling, been proposed standard protocol for diagnostics therapeutics.