EGFR-Family Expression and Implications for Targeted Radionuclide Therapy

作者: Jörgen Carlsson

DOI: 10.1007/978-1-4020-8696-0_3

关键词: Prostate cancerProstateCancer researchEpidermal growth factor receptorBreast cancerPrimary tumorPathologyReceptorReceptor expressionGliomaMedicine

摘要: High expression in the primary tumor of receptors EGFR-family is most often also accompanied by a similar high corresponding metastases. This makes these interesting as putative targets for targeted radionuclide therapy metastases and disseminated cells. The all four family members, EGFR, HER2, HER3 HER4 reviewed this chapter. Studies on breast, urinary bladder, colorectal, prostate, head neck, esophageal glioma tumors are described possible strategies discussed. Quantification receptor influence genomic stability

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