Cellular uptake of radioiodine delivered by trastuzumab can be modified by the addition of epidermal growth factor.
作者： Erika Nordberg , Ann-Charlott Steffen , Mikael Persson , Åsa L Sundberg , Jörgen Carlsson
DOI: 10.1007/S00259-005-1761-8
关键词: Trastuzumab 、 Cancer research 、 Endocrinology 、 Epidermal growth factor 、 Internal medicine 、 Medicine
摘要: Purpose The purpose of this study was to analyse whether non-radiolabelled epidermal growth factor (EGF) can modify the cellular uptake 125I when delivered as [125I]trastuzumab. used a marker for diagnostically and therapeutically more interesting isotopes 123I (SPECT), 124I (PET) 131I (therapy).
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