Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
作者： Richard Bayliss , Teresa Sardon , Isabelle Vernos , Elena Conti
DOI: 10.1016/S1097-2765(03)00392-7
关键词: Kinase 、 Aurora Kinase A 、 Biology 、 Phosphothreonine 、 MAP2K7 、 Aurora A kinase 、 Spindle apparatus 、 Cell biology 、 Integrin-linked kinase 、 Cyclin-dependent kinase 2
摘要: … domain of TPX2 sufficient to interact with Aurora-A. The Aurora-A binding domain of TPX2 has … We conclude that residues 1–43 of human TPX2 are necessary and sufficient for Aurora-A …
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