作者: Michael J. Morykwas , Denise M. Voignier , Louis C. Argenta , Jordan L. Simpson , Joseph A. Molnar
DOI:
关键词: Burn wound 、 Surgery 、 Multicenter trial 、 Thermal injury 、 Pain medication 、 Edema 、 Burned skin 、 Medicine 、 Thermal burn 、 Silver sulfadiazine
摘要: Objective: This article reports the first application of subatmospheric pressure management to a deep, partial-thickness human thermal burn. Methods: After cleaning wound, decision was made treat hand and distal forearm with (V.A.C., KCI, Inc, San Antonio, Tex). The sponge applied directly burned skin without additional interface at approximately 6 hours after injury. dressing maintained continuous negative 125 mm Hg over next 40 hours, interruption only for routine clinical evaluation 5, 16, 24 initiation treatment. accomplished by opening completely changing it. treatment tolerated well patient, requiring no excessive pain medication. stopped, wound appeared be indeterminate depth patient started on twice daily applications silver sulfadiazine. Results: impression this time that burn had not progressed but stabilized minimal edema. He followed as an outpatient returned work 8 weeks. At 4 weeks postinjury, his functional also more normal, less hyperemia than adjacent areas treated topical antibacterials. Conclusion: present case does prove prevents progression. However, when combined previously reported laboratory studies it suggests need further research. Currently, prospective, randomized, blinded, controlled multicenter trial is underway evaluate importance these observations.