Immunoglobulin structure--function correlates: antigen binding and idiotypes.

摘要: During the past few years our understanding of mechanisms involved in generation antibody diversity has greatly increased from studies monoclonal antibodies (hybridomas) and use recombinant DNA technology. While much attention appropriately been focused on these developments, it is nonetheless surprising how little we actually know about function molecules at molecular level. Since assume that primary role to bind antigens, obvious a detailed analysis this process essential an by which carry out their biological functions.