Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion.
作者： Stella Pelengaris , Trevor Littlewood , Michael Khan , George Elia , Gerard Evan
DOI: 10.1016/S1097-2765(00)80350-0
关键词: Biology 、 Lesion 、 Papillomatosis 、 Apoptosis 、 Epidermis (botany) 、 Cell growth 、 Actinic keratosis 、 Phenotype 、 Homeostasis 、 Cancer research 、 Immunology
摘要: … of differentiation are induced by c-Myc to reenter the cell cycle and proliferate whereas more differentiated granular cells instead become large hypergranular cells in which nuclear …
elsevier.com
sci-hub.se 参考文章(58)
Brinster Rl, Quaife Cj, Pinkert Ca, Sandgren Ep, Palmiter Rd, Oncogene-induced liver neoplasia in transgenic mice. Oncogene. ,vol. 4, pp. 715- ,(1989)
D S Askew, J L Cleveland, B C Simmons, R A Ashmun, Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene. ,vol. 6, pp. 1915- 1922 ,(1991)
S.D. Morgenbesser, N. Schreiber-Agus, M. Bidder, K.A. Mahon, P.A. Overbeek, J. Horner, R.A. DePinho, Contrasting roles for c-Myc and L-Myc in the regulation of cellular growth and differentiation in vivo. The EMBO Journal. ,vol. 14, pp. 743- 756 ,(1995) , 10.1002/J.1460-2075.1995.TB07053.X
A G Quinn, Ultraviolet radiation and skin carcinogenesis. British Journal of Hospital Medicine. ,vol. 58, pp. 261- 264 ,(1997)
Michael Rieger, Werner W. Franke, Identification of an orthologous mammalian cytokeratin gene. High degree of intron sequence conservation during evolution of human cytokeratin 10. Journal of Molecular Biology. ,vol. 204, pp. 841- 856 ,(1988) , 10.1016/0022-2836(88)90045-9
Henry Hennings, Adam B. Glick, Arin K. Weiner, Stuart H. Yuspa, Tamar Tennenbaum, Adam J. Belanger, The Suprabasal Expression of α6β4 Integrin Is Associated with a High Risk for Malignant Progression in Mouse Skin Carcinogenesis Cancer Research. ,vol. 53, pp. 4803- 4810 ,(1993)
Gwendolyn Gilliard, Alejandro Peralta Soler, Thomas G. O'Brien, Louis C. Megosh, Ornithine Decarboxylase Overexpression Is a Sufficient Condition for Tumor Promotion in Mouse Skin Cancer Research. ,vol. 57, pp. 2630- 2637 ,(1997)
G I Evan, G K Lewis, G Ramsay, J M Bishop, Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Molecular and Cellular Biology. ,vol. 5, pp. 3610- 3616 ,(1985) , 10.1128/MCB.5.12.3610
Martin Eilers, Didier Picard, Keith R. Yamamoto, J. Michael Bishop, Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells Nature. ,vol. 340, pp. 66- 68 ,(1989) , 10.1038/340066A0
Bruno Amati, Hartmut Land, Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death. Current Opinion in Genetics & Development. ,vol. 4, pp. 102- 108 ,(1994) , 10.1016/0959-437X(94)90098-1