Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular Oncology

作者: L. M. Ellis , D. J. Hicklin

DOI: 10.1158/1078-0432.CCR-09-1070

关键词: Predictive biomarkerPharmacologyBioinformaticsPatient survivalTargeted therapyAcquired resistanceCancerNovel agentsIntrinsic resistanceMolecular oncologyMedicine

摘要: The advent of targeted therapy for treatment of human cancers has added significantly to our armamentarium as we strive to prolong patient survival while minimizing toxicity. In cancers …

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