Expression of the HER1–4 family of receptor tyrosine kinases in breast cancer
作者： Caroline J Witton , Jonathan R Reeves , James J Going , Timothy G Cooke , John MS Bartlett
DOI: 10.1002/PATH.1370
关键词: Immunohistochemistry 、 Tyrosine kinase 、 Breast cancer 、 Receptor tyrosine kinase 、 Cancer research 、 Signal transduction 、 Growth factor receptor 、 HER2/neu 、 Estrogen receptor 、 Biology
摘要: … We observed an inverse relationship between HER1 and ER expression, and HER1 … studies of HER1 (EGFR) in breast cancer also demonstrated a negative relationship between HER1 …
sci-hub.se 参考文章(66)
Nita J. Maihle, Hakjoo Lee, Robert W. Akita, Mark X. Sliwkowski, A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4. Cancer Research. ,vol. 61, pp. 4467- 4473 ,(2001)
M Dowsett, Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer. Endocrine-related Cancer. ,vol. 8, pp. 191- 195 ,(2001) , 10.1677/ERC.0.0080191
N Prenzel, O M Fischer, S Streit, S Hart, A Ullrich, The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocrine-related Cancer. ,vol. 8, pp. 11- 31 ,(2001) , 10.1677/ERC.0.0080011
D. Slamon, G. Clark, S. Wong, W. Levin, A Ullrich, W. McGuire, Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene Science. ,vol. 235, pp. 177- 182 ,(1987) , 10.1126/SCIENCE.3798106
Tracy G. Ram, Stephen P. Ethier, Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification. Cell Growth & Differentiation. ,vol. 7, pp. 551- 561 ,(1996)
Gerard A. Rodrigues, Marco Falasca, Zhongtao Zhang, Siew Hwa Ong, Joseph Schlessinger, A Novel Positive Feedback Loop Mediated by the Docking Protein Gab1 and Phosphatidylinositol 3-Kinase in Epidermal Growth Factor Receptor Signaling Molecular and Cellular Biology. ,vol. 20, pp. 1448- 1459 ,(2000) , 10.1128/MCB.20.4.1448-1459.2000
W J Gullick, The Type 1 growth factor receptors and their ligands considered as a complex system. Endocrine-related Cancer. ,vol. 8, pp. 75- 82 ,(2001) , 10.1677/ERC.0.0080075
Peter M Siegel, Eamonn D Ryan, Robert D Cardiff, William J Muller, Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer The EMBO Journal. ,vol. 18, pp. 2149- 2164 ,(1999) , 10.1093/EMBOJ/18.8.2149
Lisa Coussens, Teresa L Yang-Feng, Yu-Cheng Liao, Ellson Chen, Alane Gray, John McGrath, Peter H Seeburg, Towia A Libermann, Joseph Schlessinger, Uta Francke, Arthur Levinson, Axel Ullrich, Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science. ,vol. 230, pp. 1132- 1139 ,(1985) , 10.1126/SCIENCE.2999974
Melody A. Cobleigh, Charles L. Vogel, Debu Tripathy, Nicholas J. Robert, Susy Scholl, Louis Fehrenbacher, Janet M. Wolter, Virginia Paton, Steven Shak, Gracie Lieberman, Dennis J. Slamon, Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease Journal of Clinical Oncology. ,vol. 17, pp. 2639- 2648 ,(1999) , 10.1200/JCO.1999.17.9.2639