Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene.
作者： Lisa Coussens , Teresa L Yang-Feng , Yu-Cheng Liao , Ellson Chen , Alane Gray
关键词: Receptor tyrosine kinase 、 Molecular biology 、 AXL receptor tyrosine kinase 、 Tyrosine kinase 、 Tropomyosin receptor kinase B 、 Biology 、 AKT2 、 Tropomyosin receptor kinase C 、 ROR1 、 Platelet-derived growth factor receptor
摘要: A novel potential cell surface receptor of the tyrosine kinase gene family has been identified and characterized by molecular cloning. Its primary sequence is very similar to that human epidermal growth factor v-erbB oncogene product; chromosomal location for this protein coincident with neu oncogene, which suggests two genes may be identical.
sciencemag.org
elsevier.com
harvard.edu
core.ac.uk
mpg.de参考文章(55)
S Jacobs, F C Kull, H S Earp, M E Svoboda, J J Van Wyk, P Cuatrecasas, Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor. Journal of Biological Chemistry. ,vol. 258, pp. 9581- 9584 ,(1983) , 10.1016/S0021-9258(17)44530-3
Edwin Southern, [9] Gel electrophoresis of restriction fragments Methods in Enzymology. ,vol. 68, pp. 152- 176 ,(1979) , 10.1016/0076-6879(79)68011-4
M Kasuga, Y Zick, D L Blith, F A Karlsson, H U Häring, C R Kahn, Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine. Journal of Biological Chemistry. ,vol. 257, pp. 9891- 9894 ,(1982) , 10.1016/S0021-9258(18)33955-3
Y Zick, M Kasuga, C R Kahn, J Roth, Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system. Journal of Biological Chemistry. ,vol. 258, pp. 75- 80 ,(1983) , 10.1016/S0021-9258(18)33222-8
B Vennström, L Fanshier, C Moscovici, J M Bishop, Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells. Journal of Virology. ,vol. 36, pp. 575- 585 ,(1980) , 10.1128/JVI.36.2.575-585.1980
S J Anderson, M Furth, L Wolff, S K Ruscetti, C J Sherr, Monoclonal antibodies to the transformation-specific glycoprotein encoded by the feline retroviral oncogene v-fms. Journal of Virology. ,vol. 44, pp. 696- 702 ,(1982) , 10.1128/JVI.44.2.696-702.1982
Charles J. Sherr, Carl W. Rettenmier, Rosalba Sacca, Martine F Roussel, A. Thomas Look, E. Richard Stanley, The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1 Cell. ,vol. 41, pp. 665- 676 ,(1985) , 10.1016/S0092-8674(85)80047-7
M Kasuga, F. Karlsson, C. Kahn, Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor Science. ,vol. 215, pp. 185- 187 ,(1982) , 10.1126/SCIENCE.7031900
Uta Francke, Bertold Francke, Requirement of the human chromosome 11 long arm for replication of herpes simplex virus type 1 in nonpermissive Chinese hamster x human diploid fibroblast hybrids. Somatic Cell and Molecular Genetics. ,vol. 7, pp. 171- 191 ,(1982) , 10.1007/BF01567656
Tony Hunter, Nicholas Ling, Jonathan A. Cooper, Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane Nature. ,vol. 311, pp. 480- 483 ,(1984) , 10.1038/311480A0