Mechanisms of Disease: signal transduction in lung carcinogenesis—a comparison of smokers and never-smokers
作者： Giannis Mountzios , Pierre Fouret , Jean-Charles Soria
DOI: 10.1038/NCPONC1181
关键词: Pathogenesis 、 Disease 、 Neoplastic transformation 、 Pathology 、 Signal transduction 、 Medicine 、 Lung 、 Palliative care 、 Transduction (genetics) 、 Carcinogenesis 、 Cancer research
摘要: Our understanding of the pathogenesis tobacco-related lung carcinogenesis is improving but molecular mechanisms neoplastic transformation in never-smokers have not yet been elucidated. Mountzios et al. describe best characterized signaling pathways that are implicated transduction proliferative signals, and discuss differences characteristics smokers never-smokers.
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