EGFR Tyrosine Kinase Domain Mutations Are Detected in Histologically Normal Respiratory Epithelium in Lung Cancer Patients

作者: Ximing Tang , Hisayuki Shigematsu , B. Nebiyou Bekele , Jack A. Roth , John D. Minna

DOI: 10.1158/0008-5472.CAN-05-1705

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摘要: … are early events in the pathogenesis of lung adenocarcinomas, we tested for the presence of EGFR mutations in histologically … DNA was extracted from microdissected tissue obtained …

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