BRAF and RAS mutations in human lung cancer and melanoma
作者： Marcia S Brose , Patricia Volpe , Michael Feldman , Madhu Kumar , Irum Rishi
DOI:
关键词: Malignant transformation 、 Targeted therapy 、 Kinase 、 Proto-Oncogene Proteins B-raf 、 Biology 、 Cancer research 、 Lung cancer 、 Carcinoma 、 Melanoma 、 Mutation
摘要: … Three BRAF mutations identified in this study are novel, altering residues important in AKT-mediated BRAF phosphorylation and suggesting that disruption of AKT-induced BRAF …
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