The association between HLA class I alleles and measles vaccine-induced antibody response: evidence of a significant association.
作者： Gregory A Poland , Robert M Jacobson , Daniel Schaid , S Breanndan Moore , Steven J Jacobsen
DOI: 10.1016/S0264-410X(98)00017-6
关键词: Virology 、 Antibody 、 Immunology 、 Morbillivirus 、 Vaccine failure 、 Measles virus 、 Measles vaccine 、 Allele 、 Human leukocyte antigen 、 Measles 、 Biology
摘要: While the Moraten strain measles vaccine is an excellent, safe, and immunogenic vaccine, failure occurs, presumably when individual develops inadequate immune response. In this study, we examined association of HLA class I genes vaccine-induced antibody levels. We found that allele distribution HLA-B alleles differed between non-responders hyper-responders (p = 0.002). Several were associated with non-response (HLA-B13, -B44, -C5); whereas several other hyper-response (HLA-B7 -B51). addition, more likely to be homozygous than normal responders (odds ratio 2.1), 3.7, p 0.031 Mantel-Haenzel for trend). Finally, evidence dose-response phenomenon HLA-B7. conclude there are important associations levels following immunization.
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sci-hub.se 参考文章(20)
E. Norrby, The paradigms of measles vaccinology. Current Topics in Microbiology and Immunology. ,vol. 191, pp. 167- 180 ,(1995) , 10.1007/978-3-642-78621-1_11
Fred Brown, Vaccines '97 : Molecular approaches to the control of infectious diseases Cold Spring Harbor Laboratory Press. ,(1997)
John J. Monaco, PATHWAYS FOR THE PROCESSING AND PRESENTATION OF ANTIGENS TO T CELLS Journal of Leukocyte Biology. ,vol. 57, pp. 543- 547 ,(1995) , 10.1002/JLB.57.4.543
Hong-Yuan Hsu, Mei-Hwei Chang, Hong-Nerng Ho, Rhong-Phong Hsieh, Shyh-Dye Lee, Ding-Shinn Chen, Chin-Yun Lee, Kue-Hsiung Hsieh, Association of HLA-DR14-DR52 with low responsiveness to hepatitis B vaccine in Chinese residents in Taiwan Vaccine. ,vol. 11, pp. 1437- 1440 ,(1993) , 10.1016/0264-410X(93)90173-U
Eric O. Long, Steven Jacobson, Pathways of viral antigen processing and presentation to CTL: defined by the mode of virus entry? Immunology Today. ,vol. 10, pp. 45- 48 ,(1989) , 10.1016/0167-5699(89)90303-4
Mary S Hayney, Gregory A Poland, Patricia Dimanlig, Daniel J Schaid, Robert M Jacobson, James J Lipsky, Polymorphisms of the TAP2 gene may influence antibody response to live measles vaccine virus. Vaccine. ,vol. 15, pp. 3- 6 ,(1997) , 10.1016/S0264-410X(96)00133-8
W. Suh, M. Cohen-Doyle, K Fruh, K Wang, P. Peterson, D. Williams, Interaction of MHC class I molecules with the transporter associated with antigen processing Science. ,vol. 264, pp. 1322- 1326 ,(1994) , 10.1126/SCIENCE.8191286
Thomas Spies, Robert DeMars, Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter. Nature. ,vol. 351, pp. 323- 324 ,(1991) , 10.1038/351323A0
Alain Townsend, John Trowsdale, The transporters associated with antigen presentation Seminars in Cell Biology. ,vol. 4, pp. 53- 61 ,(1993) , 10.1006/SCEL.1993.1007
Peter J. Krause, Measles-specific lymphocyte reactivity and serum antibody in subjects with different measles histories. JAMA Pediatrics. ,vol. 134, pp. 567- 571 ,(1980) , 10.1001/ARCHPEDI.1980.02130180025008