Simian-human immunodeficiency virus-associated nephropathy in macaques.
作者： Edward B. Stephens , Chunqiao Tian , Steven B. Dalton , Vincent H. Gattone
DOI: 10.1089/08892220050117050
关键词: Viral disease 、 Virus 、 T cell 、 Virology 、 Pigtail macaque 、 Lentivirus 、 Macaque 、 Simian immunodeficiency virus 、 Renal pathology 、 Immunology 、 Biology
摘要: A number of chimeric simian-human immunodeficiency virus (SHIV) viruses containing tat, rev, vpu, and env from HIV-1 (strain HXBc2) in a genetic background simian (SIVmac239) have been derived the parental nonpathogenic SHIV-4 virus. In this article we examine renal pathology associated with derivation these pathogenic SHIV strains. The first SHIVs, SHIVKU-1, is rapid CD4+ T cell loss opportunistic infections AIDS, but only one four infected pigtail macaques examined has developed significant pathology. macaque consists diffuse increase matrix core each lobule collapsed glomerular capillries, which similar to changes reported HIVAN. Passage into rhesus yielded SHIVKU-2, results three inoculated <10% glomeruli are involved. molecular clone SHI...
sci-hub.se 参考文章(42)
Letvin Nl, Li J, Sodroski J, Lord Ci, Haseltine W, Infection of cynomolgus monkeys with a chimeric HIV-1/SIVmac virus that expresses the HIV-1 envelope glycoproteins. Journal of Acquired Immune Deficiency Syndromes. ,vol. 5, pp. 639- 646 ,(1992)
DEAN A. REGIER, RONALD C. DESROSIERS, The Complete Nucleotide Sequence of a Pathogenic Molecular Clone of Simian Immunodeficiency Virus AIDS Research and Human Retroviruses. ,vol. 6, pp. 1221- 1231 ,(1990) , 10.1089/AID.1990.6.1221
Edward B. Stephens, Chunqiao Tian, Zhuang Li, Opendra Narayan, Vincent H. Gattone, Rhesus macaques infected with macrophage-tropic simian immunodeficiency virus (SIVmacR71/17E) exhibit extensive focal segmental and global glomerulosclerosis. Journal of Virology. ,vol. 72, pp. 8820- 8832 ,(1998) , 10.1128/JVI.72.11.8820-8832.1998
S V Joag, Z Li, L Foresman, E B Stephens, L J Zhao, I Adany, D M Pinson, H M McClure, O Narayan, Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques. Journal of Virology. ,vol. 70, pp. 3189- 3197 ,(1996) , 10.1128/JVI.70.5.3189-3197.1996
VINCENT H. GATTONE, CHUNQIAO TIAN, WU ZHUGE, MANISHA SAHNI, OPENDRA NARAYAN, EDWARD B. STEPHENS, SIV-associated nephropathy in rhesus macaques infected with lymphocyte-tropic SIVmac239. AIDS Research and Human Retroviruses. ,vol. 14, pp. 1163- 1180 ,(1998) , 10.1089/AID.1998.14.1163
Edward B. Stephens, Sampa Mukherjee, Manisha Sahni, Wu Zhuge, Ravi Raghavan, Dinesh K. Singh, Kevin Leung, Bruce Atkinson, Zhuang Li, Sanjay V. Joag, Zhen Qian Liu, Opendra Narayan, A Cell-Free Stock of Simian–Human Immunodeficiency Virus That Causes AIDS in Pig-Tailed Macaques Has a Limited Number of Amino Acid Substitutions in Both SIVmacand HIV-1 Regions of the Genome and Has Altered Cytotropism Virology. ,vol. 231, pp. 313- 321 ,(1997) , 10.1006/VIRO.1997.8534
Stuart A. Lipton, Similarity of neuronal cell injury and death in AIDS dementia and focal cerebral ischemia: potential treatment with NMDA open-channel blockers and nitric oxide-related species. Brain Pathology. ,vol. 6, pp. 507- 517 ,(1996) , 10.1111/J.1750-3639.1996.TB00879.X
Zhen Qian Liu, Sampa Muhkerjee, Manisha Sahni, Coleen McCormick-Davis, Kevin Leung, Zhaung Li, Vincent H. Gattone, Chinqiao Tian, Robert W. Doms, Trevor L. Hoffman, Ravi Raghavan, Opendra Narayan, Edward B. Stephens, Derivation and Biological Characterization of a Molecular Clone of SHIVKU-2 That Causes AIDS, Neurological Disease, and Renal Disease in Rhesus Macaques Virology. ,vol. 260, pp. 295- 307 ,(1999) , 10.1006/VIRO.1999.9812
D. C. Adamson, B. Wildemann, M. Sasaki, J. D. Glass, J. C. McArthur, V. I. Christov, T. M. Dawson, V. L. Dawson, Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41. Science. ,vol. 274, pp. 1917- 1921 ,(1996) , 10.1126/SCIENCE.274.5294.1917
Annie Lannuzel, Marc Tardieu, Christiane Hery, Jean Vianney Barnier, Jean Didier Vincent, Bernard Guibert, Huynh Van Tan, Francoise Gray, Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human neurons. Annals of Neurology. ,vol. 42, pp. 847- 856 ,(1997) , 10.1002/ANA.410420605