The efficacy of surgical treatment of recurrent or persistent cervical cancer that develops in a previously irradiated field: a monoinstitutional experience.

作者: Seiji Mabuchi , Yuri Matsumoto , Naoko Komura , Masaaki Sawada , Mie Tanaka

DOI: 10.1007/S10147-017-1134-X

关键词: Positive Surgical MarginSalvage surgerySurgeryPalliative careSurgical oncologyCervical cancerMedicinePrognostic factorSurgical treatmentRecurrent disease

摘要: There are no guidelines about the selection of recurrent cervical cancer patients for salvage surgery. Patients who developed or persistent in a previously irradiated field and were subsequently treated with surgery (the group) palliative care alone identified. Patient characteristics, treatment-related complications, survival retrospectively compared between two groups. A total 79 (surgery group, n = 51; n = 28) In intraoperative complications deaths occurred. Eleven (21.6%) experienced severe postoperative complications. After median follow-up period 41.5 months, 23 (45.1%) had disease, predominantly at distant sites, 19 (37.3%) died disease progression. The estimated 3-year progression-free (PFS) overall rates group 50.4 56.5%, respectively. all Positive surgical margins lymph node metastasis found to be independent prognostic factors PFS group. Among one poor factor, survived significantly longer than those However, among 2 factors, displayed similar periods. Salvage is curative treatment patients. considering its high complication rate, should only offered carefully selected

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