Methods and arrays for controlled manipulation of dna and chromatin fragments for genetic and epigenetic analysis
作者： Harold G. Craighead , Harvey C. Tian , Aline Cerf
DOI:
关键词: High resolution imaging 、 Histone 、 DNA 、 Molecular biology 、 Epigenetic Analysis 、 Biology 、 Nucleic acid 、 Cell biology 、 Chromatin
摘要: The present invention relates to methods and arrays for use in high resolution imaging of individual nucleic acid molecules chromatin fragments, including native fragments. In one aspect, the a array that includes transfer platform having support surface layered on support. also plurality elongated fragments coupled an orderly pattern suitable include both DNA histones.
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