Does adding milk remove the benefits of your daily cuppa

作者: S. Stanner

DOI: 10.1111/J.1467-3010.2007.00636.X

关键词: SurgeryOral ingestionTea consumptionProspective cohort studyGreen teaMyocardial infarctionBlack teaToxicologyConfoundingHeart diseaseMedicine

摘要: . 2006). Thisinverse association was stronger in women; those con-suming at least five cups a day were 31% less likely todie from cardiovascular disease than drinking onecup or less.A meta-analysis based on ten prospective cohort stud-ies and seven case–control studies, concluded that anincrease daily black tea consumption of three cupsdecreased the risk myocardial infarction by 11% [rel-ative 0.89, 95% confidence interval (CI) 0.79–1.01], although there evidence publication biasand geographical differences with benefits seen prima-rily studies continental Europe (Peters et al. 2001).In contrast, an inverse between drinkingand heart has not been demonstrated UKstudies. In fact, Woodward Tunstall-Pedoe (1999)found modest positive relationship con-sumption all-cause mortality, including coronaryheart Scottish Heart Study. However, thisstudy failed to control for important confounders asso-ciated recent review ofthe supported regular teaconsumption coronary prevention(Gardner 2007).Some have also suggested consump-tion may be associated lower mortality amongindividuals established disease. Forexample, Mukamal (2002) followed 1900 patientswho had suffered 3.8 yearsand reported cardiovascu-lar among moderate (<14 cups/week) andheavy drinkers (14 more comparedwith non-drinkers after controlling number clin-ical sociodemographic characteristics (hazard ratiofor was0.72, CI 0.55–0.94 heavy was0.56, 0.37–0.84).In vitro vivo thisreduced due antioxidant, anti-inflam-matory, antithrombogenic vasodilating effects oftea polyphenols. Tea is rich polyphenolic com-pounds flavonoids, catechins (particularly epi-gallocatechin-3-gallate), flavonols, theaflavins andthearubigins. Green leaves contain catechinsowing their high epigallocatechin-3-gallate content,while leaves, which undergo oxidation duringmanufacturing, complex thearubigins andtheaflavins (British Nutrition Foundation 2003). fla-vonoids are released when boiling water added andare known rapidly absorbed into circulationfollowing oral ingestion. Human intervention trials sug-gest (up six per day)impacts significantly plasma antioxidant capacity(Rietveld & Wiseman 2003), methodologicaldifferences, example assay methods, make studiesdifficult compare. There thisantioxidant capacity flavonoids improveendothelial function, sensitive parameter vascularwall homeostasis, response varies betweenindividuals (Hodgson 2006).Flavonoids found other foods beverages,such as cocoa, fruits vegetables red wine, buttea dietary source. UK, one studyestimated account 82% total flavonoidintake (Hertog 1997). Although no long-term ran-

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