Exercise increases endostatin in circulation of healthy volunteers.

摘要: Background Physical inactivity increases the risk of atherosclerosis. However, molecular mechanisms this relation are poorly understood. A recent report indicates that endostatin, an endogenous angiostatic factor, inhibits progression atherosclerosis, and suggests reducing intimal atherosclerotic plaque tissue neovascularization can inhibit atherosclerosis in animal models. We hypothesize exercise elevate circulatory endostatin level. Hence, protect against one