Therapeutic Concentrations of Tacrolimus Do Not Interfere With Endothelial Nitric Oxide Synthesis in Rat Thoracic Aortas and Coronary Arteries

作者: Cenk Can , Ayşe Erol , Mehtap Çnar , Murat Olukman , Sibel Ülker

DOI: 10.1097/FJC.0B013E31811FAA8A

关键词: DrugCoronary arteriesAnesthesiaIn vivoTacrolimusMedicinePharmacologyIn vitroThoracic aortaEndothelial stem cellNitric oxideCardiology and Cardiovascular Medicine

摘要: Abstract:This study aimed to investigate the potential effect of in vivo administration immunosuppressive agent FK-506 (tacrolimus) on endothelial function rat thoracic aortas with respect nitric oxide (NO) synthesis. In vitro drug NO synthesis cultured coronary

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