CCR3 Expression Induced by IL-2 and IL-4 Functioning as a Death Receptor for B Cells

作者： Tan Jinquan , Henrik H. Jacobi , Chen Jing , Anders Millner , Eva Sten

DOI: 10.4049/JIMMUNOL.171.4.1722

关键词: Cell biology 、 Apoptosis 、 Naive B cell 、 Eotaxin 、 Chemokine 、 Programmed cell death 、 Molecular biology 、 Interleukin 4 、 Biology 、 B cell 、 CD19

摘要: We report that CCR3 is not expressed on freshly isolated peripheral and germinal B cells, but is up-regulated after stimulation with IL-2 and IL-4 (∼ 98% CCR3+). Ligation of CCR3 by …

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