Molecular mechanisms of glioma invasiveness: the role of proteases.

作者: Jasti S. Rao

DOI: 10.1038/NRC1121

关键词: ProteasesCancer researchTumor recurrenceGliomaBiologyUrokinase Plasminogen ActivatorBrain tissuePathologyNeoplasm RecurrenceTherapeutic strategyTreatment modality

摘要: … detail the mechanisms of tumour invasiveness. Several proteases influence the malignant characteristics of gliomas — could their inhibition prove to be a useful therapeutic strategy? …

参考文章(145)
D. McCormick, Secretion of cathepsin B by human gliomas in vitro Neuropathology and Applied Neurobiology. ,vol. 19, pp. 146- 151 ,(1993) , 10.1111/J.1365-2990.1993.TB00420.X
Jennifer E. Koblinski, Julie Dosescu, Mansoureh Sameni, Kamiar Moin, Katherine Clark, Bonnie F. Sloane, Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B. Journal of Biological Chemistry. ,vol. 277, pp. 32220- 32227 ,(2002) , 10.1074/JBC.M204708200
Sajani S. Lakka, Sanjeeva Mohanam, Sushma L. Jasti, Gregory N. Fuller, Meena Gujrati, Sudha R. Kondraganti, Dzung H. Dinh, Nirmala Chandrasekar, Jasti S. Rao, W. K. A. Yung, Yoshiaki Kin, William C. Olivero, Athanassios P. Kyritsis, Stable Transfection of Urokinase-Type Plasminogen Activator Antisense Construct Modulates Invasion of Human Glioblastoma Cells Clinical Cancer Research. ,vol. 7, pp. 2519- 2526 ,(2001)
Martina Geheeb, Alejandra Perez-Cantó, Karsten Brand, Michael Sacharjat, Wolfgang Arnold, Andrew H. Baker, Alexandra Possling, Treatment of Colorectal Liver Metastases by Adenoviral Transfer of Tissue Inhibitor of Metalloproteinases-2 into the Liver Tissue Cancer Research. ,vol. 60, pp. 5723- 5730 ,(2000)
Daniel A Vallera, Chunbin Li, Ni Jin, Angela Panoskaltsis-Mortari, Walter A Hall, Targeting Urokinase-Type Plasminogen Activator Receptor on Human Glioblastoma Tumors With Diphtheria Toxin Fusion Protein DTAT Journal of the National Cancer Institute. ,vol. 94, pp. 597- 606 ,(2002) , 10.1093/JNCI/94.8.597
Jasti S. Rao, Peter A. Steck, Philip Tofilon, Douglas Boyd, Francis Ali-Osman, William G. Stetler-Stevenson, Lance A. Liotta, Raymond Sawaya, Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model Journal of Neuro-oncology. ,vol. 18, pp. 129- 138 ,(1994) , 10.1007/BF01050419
Dimpy Koul, Ranjani Parthasarathy, Ruijun Shen, Michael A Davies, Samar A Jasser, Shravan K Chintala, Jasti S Rao, Yi Sun, Etty N Benvenisite, Ta-Jen Liu, W K Alfred Yung, Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN Oncogene. ,vol. 20, pp. 6669- 6678 ,(2001) , 10.1038/SJ.ONC.1204799
Herbert Engelhard, Carol Narang, Ronald Homer, Holly Duncan, Urokinase Antisense Oligodeoxynucleotides as a Novel Therapeutic Agent for Malignant Glioma:In Vitroandin VivoStudies of Uptake, Effects and Toxicity Biochemical and Biophysical Research Communications. ,vol. 227, pp. 400- 405 ,(1996) , 10.1006/BBRC.1996.1519
Gheeyoung Choe, Lisa Jouben-Steele, Paul S. Mischel, Harry V. Vinters, Thomas J. Kremen, Timothy F. Cloughesy, Linda M. Liau, Jun K. Park, Active matrix metalloproteinase 9 expression is associated with primary glioblastoma subtype. Clinical Cancer Research. ,vol. 8, pp. 2894- 2901 ,(2002)