Differential diagnosis of multiple sclerosis.

摘要: There are a number of illnesses that can mimic multiple sclerosis (MS). This pretty much includes any pathological process reflect injury to the central nervous system either in transient or progressive basis. Typically, MS presents itself individuals their teens up late 30s. On occasion, however, one see present patients 60s. However, retrospect, many these might have had subtle manifestations younger years. Visual obscuration visual loss be manifestation retinal ischemia, migraine, optic neuritis which not evolve into clinical picture compatible with MS. Cranial neuropathy, long tract signs, sensory disturbance, and/or gait ataxia related different processes such as illicit drug use, neurosarcoidosis, neuro-Behcet's disease, neuroborreliosis, HIV-related neurosyphilis, vascular occlusive disease including vasculitis, connective tissue disorders, acute disseminated encephalomyelitis (ADEM), idiopathic transverse myelitis, neuromyelitis optica (NMO), tropical spastic paraparesis. In addition, constellation symptoms, questionable objective findings, along normal MRI imaging, CSF results, and evoked response testing, when indicated, identify conversion disorder possibly malingering. now established criteria for diagnosis MS, but initial presentations less than "textbook" nature. With advent immunomodulating therapy, it has become more important diagnose effectively earlier on course illness. Prior specific therapy astute clinicians did necessarily move alacrity establish manifestations. was recognition fact little could offered alter illness never experience further problems if they were lucky enough go permanent remission after minor exacerbation.