Microsatellite Instability in Natural Killer Cell–Like T-Cell Lymphomas in Immunocompromised and Immunocompetent Individuals

作者: Richard S. Larson , Suzanne Manning , William R. Macon , Cindy Vnencak-Jones

DOI: 10.1182/BLOOD.V89.3.1114

关键词: Microsatellite instabilityNeoplastic transformationT-cell lymphomaDNA mismatch repairNatural killer cellDNA repairMolecular biologyBiologyCancer researchMicrosatelliteT cell

摘要: To the Editor: Cells that have altered or absent DNA repair mechanisms may be more susceptible to genetic alteration and, thus, neoplastic transformation. Alteration in integrity of mismatch mechanism can measured by documenting microsatellite instability (MSI). Microsatellite

参考文章(6)
Thomas L. McCurley, Cindy L. Vnencak-Jones, Richard S. Larson, Margie A. Scott, Microsatellite Analysis of Posttransplant Lymphoproliferative Disorders: Determination of Donor/Recipient Origin and Identification of Putative Lymphomagenic Mechanism Cancer Research. ,vol. 56, pp. 4378- 4381 ,(1996)
Hans F. A. Vasen, G. Johan, A. Offerhaus, Frieda C. A. Den Hartog Jager, Fred H. Menko, Fokko M. Nagengast, Gerrit Griffioen, Ruud B. Van Hogezand, A. Peter M. Heintz, The tumour spectrum in hereditary non-polyposis colorectal cancer: A study of 24 kindreds in the netherlands International Journal of Cancer. ,vol. 46, pp. 31- 34 ,(1990) , 10.1002/IJC.2910460108
Gauri C. Bedi, William H. Westra, Homayoon Farzadegan, Paula M. Pitha, David Sidransky, Microsatellite instability in primary neoplasms from HIV+ patients Nature Medicine. ,vol. 1, pp. 65- 68 ,(1995) , 10.1038/NM0195-65
James R. Eshleman, Sanford D. Markowitz, MICROSATELLITE INSTABILITY IN INHERITED AND SPORADIC NEOPLASMS Current Opinion in Oncology. ,vol. 7, pp. 83- 89 ,(1995) , 10.1097/00001622-199507010-00013
WR Macon, ME Williams, JP Greer, RD Hammer, AD Glick, RD Collins, JB Cousar, Natural Killer-Like T-cell Lymphomas: Aggressive Lymphomas of T-Large Granular Lymphocytes Blood. ,vol. 87, pp. 1474- 1483 ,(1996) , 10.1182/BLOOD.V87.4.1474.BLOODJOURNAL8741474
David J. Weissmann, Judith A. Ferry, Nancy L. Harris, David N. Louis, Francis Delmonico, Ira Spiro, Posttransplantation Lymphoproliferative Disorders in Solid Organ Recipients Are Predominantly Aggressive Tumors of Host Origin American Journal of Clinical Pathology. ,vol. 103, pp. 748- 755 ,(1995) , 10.1093/AJCP/103.6.748