作者: Richard S. Larson , Suzanne Manning , William R. Macon , Cindy Vnencak-Jones
关键词: Microsatellite instability 、 Neoplastic transformation 、 T-cell lymphoma 、 DNA mismatch repair 、 Natural killer cell 、 DNA repair 、 Molecular biology 、 Biology 、 Cancer research 、 Microsatellite 、 T cell
摘要: To the Editor: Cells that have altered or absent DNA repair mechanisms may be more susceptible to genetic alteration and, thus, neoplastic transformation. Alteration in integrity of mismatch mechanism can measured by documenting microsatellite instability (MSI). Microsatellite