Simulation Modeling of Supported Lipid Membranes – A Review
作者： Michael Hirtz , Naresh Kumar , Lifeng Chi
DOI: 10.2174/1568026614666140118204332
关键词: Biosensor 、 Lipid bilayer 、 Molecular level 、 Membrane 、 Nanotechnology 、 Materials science 、 High temporal resolution 、 Drug delivery 、 Molecular dynamics 、 Simulation modeling
摘要: Lipid membranes are of great importance for many biological systems and biotechnological applications. One method to gain a profound understanding the dynamics in lipid their interaction with other system components is by modeling these computer simulations. Many different approaches have been undertaken this endeavor that led molecular level insights into underlying mechanisms several experimental observations processes an extremely high temporal resolution. As compared free-standing bilayers, there fewer simulation studies addressing supported membranes. Nevertheless, significantly enhanced our behavior layers employed applications spanning from biosensors drug delivery such as breathing cycle lung surfactants. In review, we give account state art methods simulations interfacial at air/water interface on solid surfaces.
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