Phase I study in cancer patients of a replication-defective avipox recombinant vaccine that expresses human carcinoembryonic antigen.

作者: John L. Marshall , Michael J. Hawkins , Kwong Y. Tsang , Ellen Richmond , James E. Pedicano

DOI: 10.1200/JCO.1999.17.1.332

关键词: MHC class IImmunologyCTL*Canarypox VectorImmunotherapyCancerVirologyPeripheral blood mononuclear cellMedicineCarcinoembryonic antigenRecombinant virus

摘要: … Studies were conducted to assess whether ALVAC-CEA had the ability to induce cytolytic T-lymphocyte (CTL) responses in patients with advanced cancer. Peripheral blood …

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