Deposition profile of antibacterial anodic silver in root canal systems of teeth.

作者: Murat Aydin , Ismail G�nay , Aykut Pelit , Mehmet Sami Serin

DOI: 10.1002/(SICI)1097-4636(199721)38:1<49::AID-JBM7>3.0.CO;2-H

关键词: Base (chemistry)ENDODONTIC PROCEDURESAntibacterial agentChemistryAtomic absorption spectroscopyDeposition (law)Root canalNuclear chemistryDentistryAnodeAntibacterial effect

摘要: Electrically activated silver was shown to have an antibacterial effect in vitro and vivo. In this study the of placing a anode root canal systems teeth examined establish base for treatment infected teeth. Pure wires were placed main canals extracted human (n = 26) whose roots partly submerged lactated Ringer's solution. Seventeen microamperes anodic direct current applied one group 15) 4 days. Then removed both cut into six sections demineralized Silver concentrations their bathing solutions measured with atomic absorption spectrophotometer. group, electrically (range, 1-30 micrograms/microL) exceeded levels (minimum inhibitory concentration, 0.1 micrograms/microL Ag) all sections, particularly middle lower sites root. The amount that leaked out found as be 0.4 +/- 0.2 fluid medium. This 10 100-fold higher than nonactivated controls.

参考文章(18)
Tamura K, Some effects of weak direct current and silver ions on experimental osteomyelitis and their clinical application. The Journal of the Japanese Orthopaedic Association. ,vol. 57, pp. 187- 197 ,(1983)
R O Becker, J A Spadaro, Treatment of orthopaedic infections with electrically generated silver ions. A preliminary report. Journal of Bone and Joint Surgery, American Volume. ,vol. 60, pp. 871- 881 ,(1978) , 10.2106/00004623-197860070-00001
DWIGHT A. WEBSTER, J. A. SPADARO, R. O. BECKER, S. KRAMER, Silver anode treatment of chronic osteomyelitis. Clinical Orthopaedics and Related Research. pp. 105- 114 ,(1981) , 10.1097/00003086-198111000-00013
G. Sundqvist, Ecology of the root canal flora Journal of Endodontics. ,vol. 18, pp. 427- 430 ,(1992) , 10.1016/S0099-2399(06)80842-3
J. A. Spadaro, T. J. Berger, S. D. Barranco, S. E. Chapin, R. O. Becker, Antibacterial Effects of Silver Electrodes with Weak Direct Current Antimicrobial Agents and Chemotherapy. ,vol. 6, pp. 637- 642 ,(1974) , 10.1128/AAC.6.5.637
J. L. Berry, J. M. Geiger, J. M. Moran, J. S. Skraba, A. S. Greenwald, Use of tricalcium phosphate or electrical stimulation to enhance the bone-porous implant interface. Journal of Biomedical Materials Research. ,vol. 20, pp. 65- 77 ,(1986) , 10.1002/JBM.820200107
Robert M. Stephan, John A. Muntz, Albert Dorfman, In Vitro Studies on Sterilization of Carious Dentin. III. Effective Penetration of Germicides into Carious Lesions Journal of the American Dental Association. ,vol. 30, pp. 1905- 1908 ,(1943) , 10.14219/JADA.ARCHIVE.1943.0386
J. A. Spadaro, Electrically enhanced osteogenesis at various metal cathodes. Journal of Biomedical Materials Research. ,vol. 16, pp. 861- 873 ,(1982) , 10.1002/JBM.820160611
Harold G. Petering, Pharmacology and toxicology of heavy metals: Silver Pharmacology & Therapeutics. Part A: Chemotherapy, Toxicology and Metabolic Inhibitors. ,vol. 1, pp. 127- 130 ,(1976) , 10.1016/0362-5478(76)90002-4
J. A. Spadaro, S. E. Chase, D. A. Webster, Bacterial inhibition by electrical activation of percutaneous silver implants. Journal of Biomedical Materials Research. ,vol. 20, pp. 565- 577 ,(1986) , 10.1002/JBM.820200504