Dissolution Rate Srudies I

作者: Paul J. Niebergall , Jere E. Goyan

DOI: 10.1002/JPS.2600520105

关键词: DissolutionContinuous recordingAnalytical chemistryTransmittanceChartChemistryPharmaceutical Science

摘要: An automatic recording apparatus was developed to follow the process of dissolution. Results were obtained as a per cent transmittance vs . time. The recorder equipped with various speed chart drive motors that permitted readings be taken from graph at intervals down 0.375sec. Several experiments performed demonstrate applicability this determination dissolution rates, and constants agreed well those by usual method removing samples pipet.

参考文章(6)
A. W. Hixson, J. H. Crowell, Dependence of Reaction Velocity upon Surface and Agitation Industrial & Engineering Chemistry. ,vol. 23, pp. 1002- 1009 ,(1931) , 10.1021/IE50260A018
Arthur A. Noyes, Willis R. Whitney, The rate of solution of solid substances in their own solutions Journal of the American Chemical Society. ,vol. 19, pp. 930- 934 ,(1897) , 10.1021/JA02086A003
L. J. Edwards, The dissolution and diffusion of aspirin in aqueous media Transactions of the Faraday Society. ,vol. 47, pp. 1191- 1210 ,(1951) , 10.1039/TF9514701191
Owen L. Davies, Statistical methods in research and production Journal of Chemical Education. ,vol. 27, pp. 582- ,(1987) , 10.1021/ED027P582.2
Cecil V. King, Reaction Rates at Solid—Liquid Interfaces Journal of the American Chemical Society. ,vol. 57, pp. 828- 831 ,(1935) , 10.1021/JA01308A011
L. Bruner, St. Tolloczko, Über die Auflösungsgeschwindigkeit fester Körper Zeitschrift für Physikalische Chemie. ,vol. 35, ,(1900) , 10.1515/ZPCH-1900-0117