Unravelling the diversity of mechanisms through which nutrition regulates body size in insects.

作者: Takashi Koyama , Christen K Mirth

DOI: 10.1016/J.COIS.2017.11.002

关键词: HormoneLongevityEcologyEvolutionary biologyInsectSignallingBiologyMatingGrowth factorPeriod (gene)Drosophila melanogaster

摘要: Insects show impressive diversity in adult body size across species, and within species is sensitive to numerous environmental conditions, particularly changes nutrition. Body insects correlates with a number of important fitness-related traits such as fecundity, longevity, stress resistance, mating success. Over the past few decades, field insect regulation has made progress towards understanding signalling pathways that regulate response These studies have shown conserved nutrition-sensitive act animals from vertebrates growth. In particular, like insulin/insulin-like growth factor (IIS) pathway Target rapamycin (TOR) respond levels dietary nutrients adjust both rate duration period. They do this not only by regulating organ growth, but also modifying rates synthesis circulating concentrations key developmental hormones. Although mechanisms through which occurs been well documented one insect, fruit fly Drosophila melanogaster, it becoming increasingly clear downstream IIS TOR alter nutrition differ between organs species. review, we highlight how organ-specific effects IIS/TOR are revealing control insects.

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