Surface modification of electrospun PCL scaffolds by plasma treatment and addition of adhesive protein to promote fibroblast cell adhesion

摘要: AbstractNanofibres fabricated from synthetic polymers via electrospinnning may be uniform and possess consistent quality; however, due to the nature of polymers, these nanofibres not serve as suitable substrates for cell adhesion. Thus, present work is aimed enhance adherence onto spun poly(ϵ-caprolactone) (PCL) scaffolds simple protein absorption, air plasma treatment immobilisation methods. The PCL fibres had average fibre diameter 475·99 ± 194·52 nm with porosity 72·29 1·90%. laminin absorbed scaffold exhibited 20% increase in adhesion compared original scaffold. With treatment, increased their sizes, but no significant change occurred porosities. treated was less hydrophobic 66% When also included, a greater observed (84...