The effects of amiodarone on thyroid hormone function: a review of the physiology and clinical manifestations.
作者： Helen L. Figge , James Figge
DOI: 10.1002/J.1552-4604.1990.TB01861.X
关键词: Thyroid 、 Triiodothyronine 、 Endocrinology 、 Drug 、 Hormone function 、 Internal medicine 、 Medicine 、 Toxicity 、 Physiology 、 Hormone 、 Amiodarone 、 Biological activity
摘要: Amiodarone, an iodinated benzofuran derivative, is used for treatment of refractory cardiac arrhythmias. Certain features the drug's structure resemble those biologically active thyroid hormone, triiodothyronine (T3). In addition, drug has a variety complex effects on hormone physiology, including number possible antagonistic function at cellular level. The occasionally causes clinically overt hyperthyroidism and hypothyroidism. We review these discuss their clinical implications.
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