Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis.
作者： H. N. Ho , M. Y. Wu , S. U. Chen , K. H. Chao , C. D. Chen
DOI: 10.1093/HUMREP/12.12.2810
关键词: Oxidative stress 、 Estrogen 、 Internal medicine 、 Peritoneal fluid 、 Endometriosis 、 Endocrinology 、 Infertility 、 Nitric oxide 、 Biology 、 Follicular phase 、 Pathophysiology
摘要: To explore the role of nitric oxide (NO) and oxidative stress in pathogenesis adhesion formation endometriosis-associated infertility, we examined peritoneal total antioxidant status (TAS) concentrations products NO metabolism women with endometriosis (early stage, n = 12; advanced 12) fertile without (n 10). Peritoneal CA 125 oestrogen progesterone were also measured to examine their contributions TAS production NO. We failed demonstrate any significant difference fluids among early stages compared during follicular phase. concentration not related 125, or progesterone. The serum, but fluid, was positively correlated severity endometriosis. volume fluid significantly increased group did increase from Their pathophysiology needs be explored further.
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