Splitting of the Ribose-Ribose Linkage of Poly(Adenosine Diphosphate-Ribose) by a Calf Thymus Extract

作者: Masanao Miwa , Takashi Sugimura

DOI: 10.1016/S0021-9258(18)61798-3

关键词: HydrolysisPoly Adenosine Diphosphate RibosePhosphoric monoester hydrolasesRibosePoly(ADP-ribose) glycohydrolaseBiochemistryStereochemistryThymus extractChemistry

摘要: Abstract Poly(ADP-Rib) was hydrolyzed by a calf thymus nuclear preparation. The reaction products were ADP-Rib and oligo(ADP-Rib). This is novel mechanism for degradation of poly(ADP-Rib).

参考文章(11)
Shuji Hasegawa, Shinji Fujimura, Yoshiko Shimizu, Takashi Sugimura, The polymerization of adenosine 5′-diphosphate-ribose moiety of NAD by nuclear enzyme: II. Properties of the reaction product Biochimica et Biophysica Acta. ,vol. 149, pp. 369- 376 ,(1967) , 10.1016/0005-2787(67)90165-7
Teruo Shima, Shinji Fujimura, Shuji Hasegawa, Yoshiko Shimizu, Takashi Sugimura, Studies on Poly Adenosine Diphosphate-Ribose VIII. A METHOD FOR PURIFICATION OF POLY ADENOSINE DIPHOSPHATE-RIBOSE Journal of Biological Chemistry. ,vol. 245, pp. 1327- 1330 ,(1970) , 10.1016/S0021-9258(18)63239-9
Hirotaka Matsubara, Shuji Hasegawa, Shinji Fujimura, Teruo Shima, Takashi Sugimura, Masamitsu Futai, Studies on Poly (Adenosine Diphosphate Ribose) Journal of Biological Chemistry. ,vol. 245, pp. 3606- 3611 ,(1970) , 10.1016/S0021-9258(18)62969-2
H Matsubara, S Fujimura, T Shima, T Sugimura, S Hasegawa, Studies on Poly(Adenosine Diphosphate Ribose) IX. DIRECTION OF HYDROLYSIS OF POLY(ADENOSINE DIPHOSPHATE RIBOSE) BY RAT LIVER PHOSPHODIESTERASE Journal of Biological Chemistry. ,vol. 245, pp. 4317- 4320 ,(1970)
Yasutomi Nishizuka, Kunihiro Ueda, Kinya Nakazawa, Osamu Hayaishi, Studies on the Polymer of Adenosine Diphosphate Ribose Journal of Biological Chemistry. ,vol. 242, pp. 3164- 3171 ,(1967) , 10.1016/S0021-9258(18)95947-8
Ronald H. Reeder, Kunihiro Ueda, Tasuku Honjo, Yasutomi Nishizuka, Osamu Hayaishi, Studies on the Polymer of Adenosine Diphosphate Ribose Journal of Biological Chemistry. ,vol. 242, pp. 3172- 3179 ,(1967) , 10.1016/S0021-9258(18)95948-X
Shinji Fujimura, Shuji Hasegawa, Yoshiko Shimizu, Takashi Sugimura, Polymerization of the adenosine 5'-diphosphate-ribose moiety of nicotinamide-adenine dinucleotide by nuclear enzyme. I. Enzymatic reactions. Biochimica et Biophysica Acta. ,vol. 145, pp. 247- 259 ,(1967) , 10.1016/0005-2787(67)90043-3
P. Chambon, J.D. Weill, J. Doly, M.T. Strosser, P. Mandel, On the formation of a novel adenylic compound by enzymatic extracts of liver nuclei Biochemical and Biophysical Research Communications. ,vol. 25, pp. 638- 643 ,(1966) , 10.1016/0006-291X(66)90502-X