Lower Total Knee Arthroplasty Revision Risk Associated With Bisphosphonate Use, Even in Patients With Normal Bone Density
作者： Robert S. Namba , Maria C.S. Inacio , T. Craig Cheetham , Richard M. Dell , Elizabeth W. Paxton
DOI: 10.1016/J.ARTH.2015.09.005
关键词: Surgery 、 Medicine 、 Bone Density Conservation Agents 、 Osteopenia 、 Periprosthetic 、 Lower risk 、 Bone density 、 Bisphosphonate 、 Dentistry 、 Osteoporosis 、 Bone mineral
摘要: Abstract Background Bisphosphonates (BPs) are associated with lower total knee arthroplasty (TKA) revision risk, but the effect of bone mineral density has not been evaluated. Methods A cohort 34,116 primary TKA patients was evaluated surgery and periprosthetic fractures as end points. BP usage exposure interest. Bone quality (normal, osteopenia, osteoporosis) patient age ( Results Of patients, 19.6% were users. In users, 0.5% underwent an aseptic revision; 0.6%, a fracture. non-BP 1.6% 0.1%, Conclusion Bisphosphonate use risk in all categories those older than 65 years. The higher for on BP.
sahmriresearch.org
elsevier.com参考文章(21)
Denise Greene, Richard M. Dell, Outcomes of an osteoporosis disease-management program managed by nurse practitioners Journal of the American Academy of Nurse Practitioners. ,vol. 22, pp. 326- 329 ,(2010) , 10.1111/J.1745-7599.2010.00515.X
T. Lin, S.-G. Yan, X.-Z. Cai, Z.-M. Ying, Bisphosphonates for periprosthetic bone loss after joint arthroplasty: a meta-analysis of 14 randomized controlled trials Osteoporosis International. ,vol. 23, pp. 1823- 1834 ,(2012) , 10.1007/S00198-011-1797-5
J. Goldhahn, D. Little, P. Mitchell, N.L. Fazzalari, I.R. Reid, P. Aspenberg, D. Marsh, Evidence for anti-osteoporosis therapy in acute fracture situations—Recommendations of a multidisciplinary workshop of the International Society for Fracture Repair Bone. ,vol. 46, pp. 267- 271 ,(2010) , 10.1016/J.BONE.2009.10.004
Holger Schünemann, Thomas A. Einhorn, Mohit Bhandari, Sohail Bajammal, Gordon H. Guyatt, Lauren Griffith, Jason W. Busse, Effect of bisphosphonates on periprosthetic bone mineral density after total joint arthroplasty: a meta-analysis Journal of Bone and Joint Surgery, American Volume. ,vol. 87, pp. 293- 301 ,(2005) , 10.2106/JBJS.D.01772
Richard M Dell, Denise Greene, David Anderson, Kathy Williams, Osteoporosis disease management: What every orthopaedic surgeon should know. Journal of Bone and Joint Surgery, American Volume. ,vol. 91, pp. 79- 86 ,(2009) , 10.2106/JBJS.I.00521
Maria Hilding, Per Aspenberg, Local peroperative treatment with a bisphosphonate improves the fixation of total knee prostheses: a randomized, double-blind radiostereometric study of 50 patients. Acta Orthopaedica. ,vol. 78, pp. 795- 799 ,(2007) , 10.1080/17453670710014572
Elizabeth W Paxton, Maria Inacio, Tamara Slipchenko, Donald C Fithian, The Kaiser Permanente National Total Joint Replacement Registry The Permanente Journal. ,vol. 12, pp. 12- 16 ,(2008) , 10.7812/TPP/08-008
Richard M Dell, Annette L Adams, Denise F Greene, Tadashi T Funahashi, Stuart L Silverman, Eric O Eisemon, Hui Zhou, Raoul J Burchette, Susan M Ott, Incidence of atypical nontraumatic diaphyseal fractures of the femur Journal of Bone and Mineral Research. ,vol. 27, pp. 2544- 2550 ,(2012) , 10.1002/JBMR.1719
Elizabeth W. Paxton, Maria C. S. Inacio, Monti Khatod, Eric J. Yue, Robert S. Namba, Kaiser Permanente National Total Joint Replacement Registry: Aligning Operations With Information Technology Clinical Orthopaedics and Related Research®. ,vol. 468, pp. 2646- 2663 ,(2010) , 10.1007/S11999-010-1463-9
Ching-Jen Wang, Jun-Wen Wang, Jih-Yang Ko, Lin-Hsiu Weng, Chung-Cheng Huang, Three-year changes in bone mineral density around the knee after a six-month course of oral alendronate following total knee arthroplasty. A prospective, randomized study. Journal of Bone and Joint Surgery, American Volume. ,vol. 88, pp. 267- 272 ,(2006) , 10.2106/JBJS.E.00051