Chapter 3 Cerebrovascular and Cardiovascular Pathology in Alzheimer's Disease

摘要: Presently, compelling evidence indicates that Alzheimer's disease (AD) is a vascular disorder with neurodegenerative consequences and should be treated as such. A substantial body of including epidemiological, pharmacotherapeutic, neuroimaging studies support the concept AD or vasocognopathy initiates brain hypoperfusion, creating neuronal energy crisis. The crisis provokes cellular molecular changes characterize this dementia. In brief review, many vascular‐related risk factors to some are preventable amenable treatment discussed. Considerable human data now point in new direction for guiding future research into AD. This open window opportunity decisive management devastating disorder.