Importance of canine distemper virus (cdv) infection in free-ranging iberian lynxes (lynx pardinus).

作者: Marina L Meli , Pascale Simmler , Valentino Cattori , Fernando Martínez , Astrid Vargas

DOI: 10.1016/J.VETMIC.2010.04.024

关键词: SerologyCanine distemperVirologyBiologyMorbillivirusSeroprevalenceCritically endangeredEndangered speciesVulpesPopulation

摘要: Canine distemper virus (CDV) is a morbillivirus that the etiological agent of one most important viral diseases affecting canids and an expanding range other carnivores. Using real-time RT-PCR, CDV RNA was detected in organs Iberian lynx (Lynx pardinus) found dead Donana National Park, Southwestern Andalusia, Spain. This finding may be great importance for conservation species; at present critically endangered wild felid. The aim study to elucidate significance population. High loads were evident lynx, suggesting involvement its death. When carnivores from same region analyzed by stone marten (Martes foina) positive. Phylogenetic analyses demonstrated high identity two CDVs close relationship European dog lineage CDV. Antibodies 14.8% 88 tested free-ranging lynxes. sample seroprevalence significantly higher lynxes Natural Space (22.9%) than Sierra Morena (5%). red fox (Vulpes vulpes) also seropositive. In conclusion, population, especially region, with sporadic cases disease. To reduce infectious pressure on this mass vaccination should considered.

参考文章(34)
Masami Mochizuki, Michiru Hashimoto, Shigeyuki Hagiwara, Yoshio Yoshida, Shinryo Ishiguro, Genotypes of Canine Distemper Virus Determined by Analysis of the Hemagglutinin Genes of Recent Isolates from Dogs in Japan Journal of Clinical Microbiology. ,vol. 37, pp. 2936- 2942 ,(1999) , 10.1128/JCM.37.9.2936-2942.1999
Karin Sekulin, Angela Hafner-Marx, Jolanta Kolodziejek, Dirk Janik, Peter Schmidt, Norbert Nowotny, Emergence of canine distemper in Bavarian wildlife associated with a specific amino acid exchange in the haemagglutinin protein Veterinary Journal. ,vol. 187, pp. 399- 401 ,(2011) , 10.1016/J.TVJL.2009.12.029
Guan-Zhu Han, Xi-Ping Liu, Si-Shen Li, Cross-species recombination in the haemagglutinin gene of canine distemper virus Virus Research. ,vol. 136, pp. 198- 201 ,(2008) , 10.1016/J.VIRUSRES.2008.04.022
R. Sobrino, M.C. Arnal, D.F. Luco, C. Gortázar, Prevalence of antibodies against canine distemper virus and canine parvovirus among foxes and wolves from Spain. Veterinary Microbiology. ,vol. 126, pp. 251- 256 ,(2008) , 10.1016/J.VETMIC.2007.06.014
P VANMOLL, S ALLDINGER, W BAUMGARTNER, M ADAMI, Distemper in wild carnivores: an epidemiological, histological and immunocytochemical study. Veterinary Microbiology. ,vol. 44, pp. 193- 199 ,(1995) , 10.1016/0378-1135(95)00012-Y
Pierre-Yves Daoust, Scott R. McBurney, Dale L. Godson, Marco W. G. van de Bildt, Albert D. M. E. Osterhaus, Canine distemper virus-associated encephalitis in free-living lynx (Lynx canadensis) and bobcats (Lynx rufus) of Eastern Canada Journal of Wildlife Diseases. ,vol. 45, pp. 611- 624 ,(2009) , 10.7589/0090-3558-45.3.611
Marina L Meli, Valentino Cattori, Fernando Martínez, Guillermo López, Astrid Vargas, Miguel A Simón, Irene Zorrilla, Alvaro Munoz, Francisco Palomares, Jose V Lopez-Bao, Josep Pastor, Ravi Tandon, Barbara Willi, Regina Hofmann-Lehmann, Hans Lutz, None, Feline leukemia virus and other pathogens as important threats to the survival of the critically endangered Iberian lynx (Lynx pardinus). PLOS ONE. ,vol. 4, ,(2009) , 10.1371/JOURNAL.PONE.0004744
M. López-Peña, S. Vázquez, N. Alemañ, A. López-Beceiro, F. Muñoz, J.L. Pereira, J.M. Nieto, Canine distemper in a genet (Gennetta gennetta), associated with endogenous lipid pneumonia. Journal of Comparative Pathology. ,vol. 124, pp. 207- 211 ,(2001) , 10.1053/JCPA.2000.0432
M. López-Peña, M. I. Quiroga, S. Vázquez, J. M. Nieto, Detection of Canine Distemper Viral Antigen in Foxes (Vulpes vulpes) in Northwestern Spain Journal of Wildlife Diseases. ,vol. 30, pp. 95- 98 ,(1994) , 10.7589/0090-3558-30.1.95