Food allergy in children: diagnosis and treatment with sodium cromoglycate.

摘要: Food allergy (FA) is a very important problem affecting numbers of infants and children with protean manifestations which are frequent challenges to the pediatrician other specialists working children. Adverse reactions food complex, frequently mediated bu IgE mechanisms, often by mechanisms. To make correct diagnosis arrive at proper therapeutic approach requires all skill physician can gather. Only an extensive knowledge various mechanisms pharmacologic agents that be used prevent or treat these adverse will allow scientifically come reasonable solution for patient. The role dietary factors in atopic dermatitis (AD) has long been subject controversies. However, it shown FA plays some AD. Therefore, management this multifaceted disorder challenge pediatricians, dermatologists, allergists. SCG, salt bis-chromone carboxylic acid, proven efficacy prophylaxis bronchial asthma, allergic rhinitis, disorders associated mast cell degranulation. drug different modes action, such as inhibition rat passive cutaneous anaphylaxis, antigen-induced histamine release from passively sensitized peritoneal cells. Recently, clinical studies indicated SCG direct effect on inflammatory cells, inhibiting either leukocyte functions (membrane receptor expression, cytotoxic capacity), "in vitro" activation human neutrophils, eosinophils monocytes. Although widely respiratory allergy, conflicting results treatment have reported several authors. We reviewed 18 papers use FA, included 341 aged 0.5-15 years. In paper we discuss 12 reporting 281 affected