Comparison of rapid office-based serology with formal laboratory-based ELISA testing for diagnosis of Helicobacter pylori gastritis

摘要: Accurate and cost-effective diagnosis ofHelicobacter pylori gastritis has taken on majorimportance. Several serologic tests for the ofH. infection are commercially available. Wecompared performance of FlexSure HP rapid IgGantibody test with conventional HM-CAP ELISA toevaluate whether qualitative office-based serology isreliable enough to replace formal laboratory-based testing. We assessed H. status byconcordance in 100 consecutive patients antralbiopsy, urease, 1 μCi[14C]ureabreath tests. Both antibody had good sensitivityand specificity (>86%). Concordance between two antibodytests occurred 87/93 (94%). Based ourdata, performed equallywell as may be a better choice initial serologicdiagnosis untreated patients.