An evaluation of whole blood testing for Helicobacter pylori infection in the Chinese population.
作者： Wong , Wong , Tang , Lai , Yuen
DOI: 10.1046/J.1365-2036.2000.00704.X
关键词:
摘要: Background: Near patient tests for Helicobacter pylori were developed to assist in the management of dyspepsia patients general practice. Most studies performed western populations. Aim: To evaluate rapid whole blood test (Flexpack HP) H. Chinese population. Methods: Consecutive dyspeptic referred upper endoscopy recruited. During endoscopy, biopsies taken from antrum and corpus urease (CLO test) histological examination. After (FlexPack was according manufacturer’s instruction. Patients then received a 13C-urea breath test. Results compared with gold standard test, histology test). Results: A total 294 consecutive gave valid Flexpack HP result interpretation. The mean age 47.7 (range 15–85) years. Analysis showed sensitivity, specificity, positive predictive value, negative value accuracy 58%, 92%, 91%, 63% 73% respectively. Conclusion: The FlexPack good specificity but lacked sensitivity. It is not sensitive enough be used practice setting test-and-treat approach population.
hku.hk
core.ac.uk
sci-hub.se 参考文章(32)
Joyann A. Kroser, Douglas O. Faigel, Emma E. Furth, David C. Metz, Comparison of rapid office-based serology with formal laboratory-based ELISA testing for diagnosis of Helicobacter pylori gastritis Digestive Diseases and Sciences. ,vol. 43, pp. 103- 108 ,(1998) , 10.1023/A:1018832306135
Graham Dy, Evans Dj, Baker Jt, Peacock J, Schrier Wh, Comparison of rapid serological tests (FlexSure HP and QuickVue) with conventional ELISA for detection of Helicobacter pylori infection. The American Journal of Gastroenterology. ,vol. 91, pp. 942- 948 ,(1996)
Wayne H Schrier, Ronald J Schoengold, Josefina T Baker, Joyce L Norell, Corey L Jaseph, Yelena Okin, Jeam Y Doe, Howard Chandler, Development of FlexSure® HP—an immunochromatographic method to detect antibodies against Helicobacter pylori Clinical Chemistry. ,vol. 44, pp. 293- 298 ,(1998) , 10.1093/CLINCHEM/44.2.293
A van der Ende, EA Rauws, M Feller, CJ Mulder, GN Tytgat, J Dankert, Heterogeneous Helicobacter pylori isolates from members of a family with a history of peptic ulcer disease Gastroenterology. ,vol. 111, pp. 638- 647 ,(1996) , 10.1053/GAST.1996.V111.PM8780568
Daniel Sadowski, Hartley Cohen, Loren Laine, Paul Greenberg, Jay Goldstein, Michael Mihalov, Alan F. Cutler, Evaluation of the FlexSure HP whole blood antibody test for diagnosis of Helicobacter pylori infection The American Journal of Gastroenterology. ,vol. 93, pp. 2119- 2123 ,(1998) , 10.1111/J.1572-0241.1998.00604.X
Natalia Akopyanz, Nickolai O. Bukanov, T.Ulf Westblom, Douglas E. Berg, PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogen Helicobacter pylori. Nucleic Acids Research. ,vol. 20, pp. 6221- 6225 ,(1992) , 10.1093/NAR/20.23.6221
Haim Shirin, Rafael Bruck, Gabriel Kenet, Zipora Krepel, Yoram Wardi, Simon Reif, Liliana Zaidel, Dikla Geva, Yona Avni, Zamir Halpern, Evaluation of a new immunochromatographic test for Helicobacter pylori IgG antibodies in elderly symptomatic patients Journal of Gastroenterology. ,vol. 34, pp. 7- 10 ,(1999) , 10.1007/S005350050209
Leen–Jan Van Doorn, Céu Figueiredo, Francis Mégraud, Salvador Pena, Peter Midolo, Dulciene Maria De Magalhães Queiroz, Fátima Carneiro, Bart Vanderborght, Maria Da Glória F. Pegado, Ricardo Sanna, Wink De Boer, Peter M. Schneeberger, Pelayo Correa, Enders K.W. Ng, John Atherton, Martin J. Blaser, Wim G.V. Quint, Geographic distribution of vacA allelic types of Helicobacter pylori. Gastroenterology. ,vol. 116, pp. 823- 830 ,(1999) , 10.1016/S0016-5085(99)70065-X
BarryJ Marshall, J Robin Warren, ElizabethD Blincow, Michael Phillips, C Stewart Goodwin, Raymond Murray, StephenJ Blackbourn, ThomasE Waters, ChristopherR Sanderson, None, Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. The Lancet. ,vol. 332, pp. 1437- 1442 ,(1988) , 10.1016/S0140-6736(88)90929-4
BCY Wong, CK Ching, SK Lam, ZL Li, BW Chen, YN Li, HJ Liu, JB Liu, BE Wang, SZ Yuan, CP Xu, XH Hou, AT Zhang, ZT Zheng, None, Differential north to south gastric cancer-duodenal ulcer gradient in China Journal of Gastroenterology and Hepatology. ,vol. 13, pp. 1050- 1057 ,(1998) , 10.1111/J.1440-1746.1998.TB00569.X