Light microscopical study of nitric oxide synthase I-positive neurons, including fibres in the vestibular nuclear complex of the cat.

作者: Vassil Papantchev , Adrian Paloff , Tatiana Christova , Dimka Hinova-Palova , Wladimir Ovtscharoff

DOI: 10.1016/J.ACTHIS.2005.01.004

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摘要: Summary Nitric oxide is a gaseous neurotransmitter that synthesized by the enzyme nitric synthase I (NOS I). At present, little known of NOS I-positive neurons in vestibular nuclear complex cat (VNCc). The aim present study was to examine morphology, distribution patterns and interconnections neurons, including fibres VNCc. Five adult cats were used as experimental animals. All anaesthetized perfused transcardially. Brains removed, postfixed, cut on freezing microtome stained three different ways. Every third section treated with Nissl method, other sections either histochemically for NADPH diaphorase or immunohistochemically I. atlas Berman (1928) orientation morphometric study. found all parts VNCc: medial nucleus (MVN); lateral (LVN); superior (SVN); inferior (IVN); X, Y, Z groups Cajal's nucleus. classified according their size (small, medium-sized, large type II) shape (oval, fusiform, triangular, pear-shaped, multipolar irregular). In every nucleus, specific neuronal population observed. SVN, number between identified. MVN, chain-like rolls small found. Tiny MVN mesencephalic reticular formation present. Our data provide information VNCc can be extrapolated mammals.

参考文章(27)
Alvin L. Berman, The brain stem of the cat : a cytoarchitectonic atlas with stereotaxic coordinates University of Wisconsin Press. ,(1968)
D V Hinova-Palova, A Paloff, T Christova, W Ovtscharoff, Topographical distribution of NADPH-diaphorase-positive neurons in the cat's claustrum. European Journal of Morphology. ,vol. 35, pp. 105- 116 ,(1997) , 10.1076/EJOM.35.2.105.13068
B. Moreno-López, M. Escudero, J.M. Delgado-García, C. Estrada, Nitric Oxide Production by Brain Stem Neurons Is Required for Normal Performance of Eye Movements in Alert Animals Neuron. ,vol. 17, pp. 739- 745 ,(1996) , 10.1016/S0896-6273(00)80205-6
M.T. Conconi, P. Bruno, A. Bonali, S. De Angeli, P.P. Parnigotto, Relationship between the proliferation of keratinocytes cultured in vitro and prostaglandin E2 Annals of Anatomy-anatomischer Anzeiger. ,vol. 178, pp. 229- 236 ,(1996) , 10.1016/S0940-9602(96)80055-0
T. M. Dawson, D. S. Bredt, M. Fotuhi, P. M. Hwang, S. H. Snyder, Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 7797- 7801 ,(1991) , 10.1073/PNAS.88.17.7797
Claire E. Sears, Simon M. Bryant, Euan A. Ashley, Craig A. Lygate, Stevan Rakovic, Helen L. Wallis, Stefan Neubauer, Derek A. Terrar, B. Casadei, Cardiac Neuronal Nitric Oxide Synthase Isoform Regulates Myocardial Contraction and Calcium Handling Circulation Research. ,vol. 92, ,(2003) , 10.1161/01.RES.0000064585.95749.6D
Bernardo Moreno-López, Miguel Escudero, Jan De Vente, Carmen Estrada, Morphological identification of nitric oxide sources and targets in the cat oculomotor system The Journal of Comparative Neurology. ,vol. 435, pp. 311- 324 ,(2001) , 10.1002/CNE.1032
Iftikhar J. Kullo, Robert S. Schwartz, Vincent J. Pompili, Masato Tsutsui, Sheldon Milstien, Lorraine A. Fitzpatrick, Zvonimir S. Katusic, Timothy O’Brien, Expression and Function of Recombinant Endothelial NO Synthase in Coronary Artery Smooth Muscle Cells Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 17, pp. 2405- 2412 ,(1997) , 10.1161/01.ATV.17.11.2405