Chemotherapy-Associated Hepatotoxicity and Hepatic Resection for Metastatic Colorectal Cancer
作者： Sam C. Wang , Michael I. D’Angelica
DOI: 10.1007/S11888-014-0218-5
关键词:
摘要: Approximately 50 % of patients with colorectal cancer will develop liver metastases. Complete resection is associated five-year overall survival and 20 % long-term cure. Use preoperative chemotherapy for resectable metastasis to the controversial. Among arguments against use resulting hepatotoxicity, which may increase risk hepatectomy. In this review, we assess liver-specific toxicity profiles most commonly used agents how affects perioperative outcomes. We also comment on neoadjuvant metastasis.
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