DNA microarrays: a powerful genomic tool for biomedical and clinical research.

摘要: Among the many benefits of Human Genome Project are new and powerful tools such as genome-wide hybridization devices referred to microarrays. Initially designed measure gene transcriptional levels, microarray technologies now used for comparing other genome features among individuals their tissues cells. Results provide valuable information on disease subcategories, prognosis, treatment outcome. Likewise, they reveal differences in genetic makeup, regulatory mechanisms, subtle variations move us closer era personalized medicine. To understand this tool, its versatility, how dramatically it is changing molecular approach biomedical clinical research, review describes technology, applications, a didactic step-by-step typical protocol, real experiment. Finally, calls attention medical community importance integrating multidisciplinary teams take advantage technology expanding applications that, slide, reveals our inheritance destiny.