How much solute is needed to inhibit the fluid to gel membrane phase transition at low hydration

作者: Thomas Lenné , Gary Bryant , Roland Holcomb , Karen L. Koster

DOI: 10.1016/J.BBAMEM.2007.01.008

关键词:

摘要: We present a quantitative study of the effect sugars on membrane gel-fluid phase transition as function sugar:lipid ratio. show that maximum occurs at around 1.5 sugar rings per molecule for both mono- and di-saccharides. theoretical model to try explain these results, discuss assumptions inherent in model.

参考文章(20)
J H Crowe, L M Crowe, J F Carpenter, C Aurell Wistrom, Stabilization of dry phospholipid bilayers and proteins by sugars. Biochemical Journal. ,vol. 242, pp. 1- 10 ,(1987) , 10.1042/BJ2420001
Karen L. Koster, Kami J. Maddocks, Gary Bryant, Exclusion of maltodextrins from phosphatidylcholine multilayers during dehydration: effects on membrane phase behaviour. European Biophysics Journal. ,vol. 32, pp. 96- 105 ,(2003) , 10.1007/S00249-003-0277-Z
M. Nakagaki, H. Nagase, H. Ueda, Stabilization of the lamellar structure of phosphatidylcholine by complex formation with trehalose Journal of Membrane Science. ,vol. 73, pp. 173- 180 ,(1992) , 10.1016/0376-7388(92)80127-6
L. B. Rockland, Saturated Salt Solutions for Static Control of Relative Humidity between 5° and 40° C. Analytical Chemistry. ,vol. 32, pp. 1375- 1376 ,(1960) , 10.1021/AC60166A055
John H. Crowe, Lois M. Crowe, John F. Carpenter, A.S. Rudolph, Christina Aurell Wistrom, B.J. Spargo, T.J. Anchordoguy, Interactions of sugars with membranes Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes. ,vol. 947, pp. 367- 384 ,(1988) , 10.1016/0304-4157(88)90015-9
Karen L. Koster, A. Carl Leopold, Sugars and Desiccation Tolerance in Seeds Plant Physiology. ,vol. 88, pp. 829- 832 ,(1988) , 10.1104/PP.88.3.829
Thomas Lenné, Gary Bryant, Christopher J. Garvey, Uwe Keiderling, Karen L. Koster, Location of sugars in multilamellar membranes at low hydration Physica B-condensed Matter. ,vol. 385, pp. 862- 864 ,(2006) , 10.1016/J.PHYSB.2006.05.127
Gary Bryant, Karen L Koster, Dehydration of solute-lipid systems: hydration forces analysis. Colloids and Surfaces B: Biointerfaces. ,vol. 35, pp. 73- 79 ,(2004) , 10.1016/J.COLSURFB.2004.02.001