Efectos cutáneos de los inhibidores del receptor del factor de crecimiento epidérmico

作者: Guillermo Guhl , Ana González-De Arriba , Esteban Daudén

DOI: 10.1016/S0001-7310(06)73407-X

关键词:

摘要: Epidermal growth factor receptor (EGFR) inhibitors are a new group of drugs used in the treatment several malignancies. Three molecules approved at moment: gefitinib and erlotinib for non-small-cell lung cancer, cetuximab colorectal cancer. These originate cutaneous side effects with high frequency: acneiform rashes, paronychia generalized xerodermia. In this paper we review these common how to manage them.

参考文章(125)
Jeffrey M Weinberg, The anti-inflammatory effects of tetracyclines. Cutis. ,vol. 75, pp. 6- 11 ,(2005)
E. Bierhoff, H. W. Seifert, T. Dirschka, Cutaneous lesions due to inhibition of epidermal growth factor receptor Pathologe. ,vol. 27, pp. 53- 56 ,(2006) , 10.1007/S00292-005-0803-0
Scheinfeld N, A comprehensive review of imatinib mesylate (Gleevec) for dermatological diseases. Journal of Drugs in Dermatology. ,vol. 5, pp. 117- 122 ,(2006)
A Ferrante, Y H Thong, Inhibition of mitogen-induced human lymphocyte proliferative responses by tetracycline analogues. Clinical and Experimental Immunology. ,vol. 35, pp. 443- ,(1979)
L Walon, Jean-Marie Lachapelle, C Gilbeau, Acneiform eruptions induced by cetuximab Annales De Dermatologie Et De Venereologie. ,vol. 130, pp. 443- 446 ,(2003)
Terry Magnuson, David W. Threadgill, John P. Sundberg, Laura A. Hansen, Stuart H. Yuspa, Margaret E. Hogan, Andrzej Dlugosz, Natalie Alexander, Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development American Journal of Pathology. ,vol. 150, pp. 1959- 1975 ,(1997)
Stanley Cohen, Epidermal growth factor Bioscience Reports. ,vol. 6, pp. 1017- 1028 ,(1986) , 10.1007/BF01141022
Ulrich Rodeck, Monika Jost, Csaba Kari, The EGF receptor - an essential regulator of multiple epidermal functions. European Journal of Dermatology. ,vol. 10, pp. 505- 510 ,(2000)