作者: Franklin H. Epstein , Barry M. Brenner , Timothy W. Meyer , Thomas H. Hostetter
DOI: 10.1056/NEJM198209093071104
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摘要: IT is now more than 30 years since Addis suggested that protein intake be restricted in patients with chronic renal insufficiency.1 His aim was not to reduce uremic symptoms but rather prevent an increase the "workload" of surviving nephrons diseased kidneys order minimize further loss function. With development and increasingly widespread availability dialysis transplantation past three decades, relatively little attention has been paid influence diet on progression disease, despite general awareness disease typically follows inexorably progressive course. In this . . .