Quantitative evaluation of genetic and environmental parameters determining antibody response induced by vaccination against bovine respiratory syncytial virus.

作者: R.G. O’Neill , J.A. Woolliams , E.J. Glass , J.L. Williams , J.L. Fitzpatrick

DOI: 10.1016/J.VACCINE.2005.11.049

关键词:

摘要: Abstract The parameters controlling IgG antibody responses induced by vaccination against bovine respiratory syncytial virus (BRSV) were investigated in 463 Holstein–Charolais crossbred cattle. Pre- and post-vaccination sera tested enzyme linked immunosorbent assays (ELISA) for BRSV-specific 2 . Year-of-birth, age, sex pre-existing significant sources of variation responses. Pre-vaccination, progeny with a higher proportion Holstein genes had total BRSV-IgG. By Day 35 post-vaccination, heritabilities peaked at 0.26 BRSV-IgG 0.36 1 There was no evidence interbreed differences between Charolais calves, post-vaccination. These results suggest that calf-sire has major heritable influence on serum levels following BRSV immunisation.

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