0.1T magnetic resonance image in the study of experimental hydrocephalus in rats. Accuracy of the method in the measurements of the ventricular size 1 Imagem de ressonância magnética de 1,0T no estudo da hidrocefalia experimental em ratos. Avaliação do método de medição do tamanho ventricular

摘要: PURPOSE: To investigate the accuracy of 1.0T Magnetic Resonance Imaging (MRI) to measure ventricular size in experimental hydrocephalus pup rats. METHODS: Wistar rats were subjected by intracisternal injection 20% kaolin (n=13). Ten remained uninjected be used as controls. At endpoint experiment animals submitted MRI brain and killed. The was assessed using three measures: ratio (VR), cortical thickness (Cx) ventricles area (VA), performed on photographs anatomical sections MRI. RESULTS: images obtained through MR present enough quality show lateral cavities but not demonstrate difference between cortex white matter, well details deep structures brain. There no statistically differences measures VR Cx (p=0.9946 p=0.5992, respectively). VA measured (p<0.0001). CONCLUSION: parameters sufficient individualize cerebral cortex, calculate when compared their respective anatomic slice.