Small molecule inhibitors of mammalian thioredoxin reductase
作者： Wenqing Cai , Liangwei Zhang , Yanlin Song , Baolin Wang , Baoxin Zhang
DOI: 10.1016/J.FREERADBIOMED.2011.10.447
关键词:
摘要: Mammalian thioredoxin reductases (TrxRs) are a family of NADPH-dependent flavoproteins with a penultimate selenocysteine residue at the carboxy-terminus. Besides their native …
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sci-hub.se 参考文章(97)
Elena Vergara, Angela Casini, Francesca Sorrentino, Olivier Zava, Elena Cerrada, Maria Pia Rigobello, Alberto Bindoli, Mariano Laguna, Paul J Dyson, Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands. ChemMedChem. ,vol. 5, pp. 96- 102 ,(2010) , 10.1002/CMDC.200900370
Jun Lu, Laura V. Papp, Jianguo Fang, Salvador Rodriguez-Nieto, Boris Zhivotovsky, Arne Holmgren, Inhibition of Mammalian Thioredoxin Reductase by Some Flavonoids: Implications for Myricetin and Quercetin Anticancer Activity Cancer Research. ,vol. 66, pp. 4410- 4418 ,(2006) , 10.1158/0008-5472.CAN-05-3310
M W Kunkel, J I Johnson, D L Kirkpatrick, G Powis, Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs. Anti-cancer Drug Design. ,vol. 12, pp. 659- 670 ,(1997)
Maria Pia Rigobello, Alberto Bindoli, Mitochondrial thioredoxin reductase purification, inhibitor studies, and role in cell signaling Methods in Enzymology. ,vol. 474, pp. 109- 122 ,(2010) , 10.1016/S0076-6879(10)74007-6
Gillian D. Paine-Murrieta, Ian Cotgreave, Charles W. Taylor, Miguel Angulo, Lars Engman, Garth Powis, Diaryl chalcogenides as selective inhibitors of thioredoxin reductase and potential antitumor agents. Anticancer Research. ,vol. 17, pp. 4599- 4605 ,(1997)
Mau Bey-Liing, Garth Powis, Inhibition of cellular thioredoxin reductase by diaziquone and doxorubicin. Relationship to the inhibition of cell proliferation and decreased ribonucleotide reductase activity. Biochemical Pharmacology. ,vol. 43, pp. 1621- 1626 ,(1992) , 10.1016/0006-2952(92)90221-4
Elias S. J. Arnér, Mikael Björnstedt, Arne Holmgren, 1-Chloro-2,4-dinitrobenzene Is an Irreversible Inhibitor of Human Thioredoxin Reductase LOSS OF THIOREDOXIN DISULFIDE REDUCTASE ACTIVITY IS ACCOMPANIED BY A LARGE INCREASE IN NADPH OXIDASE ACTIVITY Journal of Biological Chemistry. ,vol. 270, pp. 3479- 3482 ,(1995) , 10.1074/JBC.270.8.3479
Jonas Nordberg, Elias S.J. Arnér, Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4. Free Radical Biology and Medicine. ,vol. 31, pp. 1287- 1312 ,(2001) , 10.1016/S0891-5849(01)00724-9
Jerzy Jankun, Steven H. Selman, Rafal Swiercz, Ewa Skrzypczak-Jankun, Why drinking green tea could prevent cancer Nature. ,vol. 387, pp. 561- 561 ,(1997) , 10.1038/42381
Peter Wipf, Stephen M. Lynch, Anne Birmingham, Giselle Tamayo, Allan Jiménez, Nefertiti Campos, Garth Powis, Natural product based inhibitors of the thioredoxin–thioredoxin reductase system Organic and Biomolecular Chemistry. ,vol. 2, pp. 1651- 1658 ,(2004) , 10.1039/B402431A