Antimicrobial resistance patterns in Danish isolates of Flavobacterium psychrophilum

作者: Morten Sichlau Bruun , Anja Silke Schmidt , Lone Madsen , Inger Dalsgaard

DOI: 10.1016/S0044-8486(00)00310-0

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摘要: The resistance pattern of Flavobacterium psychrophilum to the antimicrobial agents used in fish farming Denmark was assessed vitro using an agar dilution method. After identification 387 isolates from clinical outbreaks rainbow trout fry syndrome (RTFS) and environment, were tested resulting antibiograms predict theoretical therapeutic efficacy evaluate if had changed as a course time. Antimicrobial included this investigation oxolinic acid (OXA), amoxicillin (AMX), potentiated sulfadiazine, oxytetracycline (OTC) florfenicol (FLO). We found that F. divided susceptible resistant clusters reflecting reduced practice when OTC AMX. most recent less AMX OXA, whereas seemed stable over last 5 years. Apparently, carries intrinsic towards sulfonamides, correlation with this, we very few isolates. All FLO. method for determining minimum inhibitory concentration (MIC) follows American guideline National Committee Clinical Laboratory Standards (NCCLS) some modifications comply growth demand fastidious bacterium. suggest future investigations use these guidelines benchmark.

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